I'm currently reading Michael Moorcock's Black Corridor published in 1969. Short and thought-provoking it's a very good read and quite SWORDesque, describing, as it does, a dying Earth. It is essentially a novel about the decay of society and the deep personal and social isolation this has caused, and tells of a man fleeing through interstellar space from Earth, where civilisation is collapsing into anarchy and wars [Wikipedia - alert! its full page contains spoilers!].
Given the plot it seems only right that an edition by Mayflower even featured SPACEX toys on its pinky cover, shown below right. Try as I might, I have been unable to find a copy of this particular paperback and on two occasions mistakenly purchased the more common black Mayflower cover, below left, despite the Amazon listings showing the SPACEX cover. Drat!
The story of the man suffering alone in deep space reminds me of the plot of Duncan Jones' film MOON. This solitary slide into mental breakdown is a popular idiom in Science Fiction.
The malaise is in fact real and called Pandorum, which is defined as "a disease founded by emotional triggers, usually found in deep space missions, a feeling of fear. Thinking you can't be saved, you may find yourself in a state of Pandorum, or extreme fear of being alone". There is a film of the same name from 2009, which I have yet to see. Have you?
What books or other publication are you reading at the moment?